Clinical experience with ciprofloxacin: analysis of a multicenter study

In a multicenter study of 36 patients treated with ciprofloxacin (mean daily dosage, 986 mg per day; mean duration of treatment, 10.8 days) for a variety of infections, 32 were microbiologically proven. Of these, bacteriologic cure and/or improvement resulted in 100% of cases. For all 36 infections clinical cure and/or improvement resulted in 97.1% of cases. A total of 13 infections were classified as chronic. Overall there were six adverse reactions reported in 4/36 (11.1%) patients. Five were considered related definitely to ciprofloxacin therapy, one was not. Therapy with ciprofloxacin was discontinued in two patients (5.5%). Two patients elected to continue ciprofloxacin therapy despite mild side effects.