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Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

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Whole-Body Diffusion Imaging Applying Simultaneous Multi-Slice Excitation.

D Kenkel¹, M C Wurnig¹, L Filli¹

¹Department of Diagnostic and Interventional Radiology, University Hospital Zurich, Switzerland.

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|January 28, 2016

Summary

This summary is machine-generated.

A new fast protocol for whole-body diffusion-weighted imaging (WB-DWI) significantly reduces scan time by up to 25.9% without compromising image quality. This advancement enhances the clinical applicability of WB-DWI for various medical assessments.

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Area of Science:

Magnetic Resonance Imaging (MRI)
Medical Imaging Techniques

Background:

Whole-body diffusion-weighted imaging (WB-DWI) is valuable for disease assessment.
Conventional WB-DWI protocols are time-consuming, limiting clinical use.

Purpose of the Study:

To evaluate the feasibility of a rapid WB-DWI protocol.
To assess a slice-accelerated echo-planar imaging sequence for WB-DWI.

Main Methods:

A slice-accelerated echo-planar imaging sequence was optimized for WB-DWI at 3T.
Eight healthy volunteers and one oncologic patient were scanned.
Image quality and apparent diffusion coefficient (ADC) values were analyzed.

Main Results:

Scan time was reduced by up to 25.9% with the accelerated protocol.
Image quality was comparable between the accelerated and conventional protocols.
ADC values were similar, with slightly higher brain ADC in the accelerated group.

Conclusions:

Slice-accelerated DWI is feasible for WB-DWI, significantly reducing scan time.
The reduced measurement time enhances the clinical applicability of WB-DWI.
Further research is needed to refine the sequence and investigate its role in oncologic disease assessment.