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Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology
Published on: March 22, 2012
Invasive aspergillosis in near drowning nonneutropenic patient
Kartik Munta1, Palepu B N Gopal2, Ajit Vigg3
1Department of Critical Care, Yashoda Hospital, Nampally, Hyderabad, Telangana, India.
Abstract:
Invasive aspergillosis in immunosuppressed people has been well documented, but to diagnose and treat in an immunocompetent individual after near drowning, it requires early suspicion and proper empirical treatment. We report a case diagnosed to have invasive aspergillosis with systemic dissemination of the infection to the brain, gluteal muscles, and kidneys after a fall in a chemical tank of a paper manufacturing company. He was ventilated for acute respiratory distress syndrome and managed with antibiotics and vasopressors. Due to nonresolving pneumonia and positive serum galactomannan, trans-tracheal biopsy was performed which confirmed invasive aspergillosis and was treated with antifungals. With the availability of galactomannan assay and better radiological investigative modalities, occurrence of such invasive fungal infections in cases of drowning patients should be considered early in such patients and treated with appropriate antifungals.
Insights
Invasive aspergillosis can occur in immunocompetent individuals after near-drowning incidents. Early suspicion and treatment with antifungals are crucial for better outcomes in these rare cases.
Area of Science:
- Medicine
- Infectious Diseases
- Mycology
Background:
- Invasive aspergillosis is typically seen in immunosuppressed patients.
- Diagnosis and treatment in immunocompetent individuals after near-drowning are challenging.
- This case highlights a rare presentation following a chemical tank fall.
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