Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

8.9K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
8.9K
Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

6.5K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
6.5K
Infertility in Females01:28

Infertility in Females

5.0K
Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of...
5.0K
Infertility in Males01:23

Infertility in Males

680
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
680
The Thyroid Gland01:23

The Thyroid Gland

8.6K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
8.6K
Major Hormones and Their Functions01:27

Major Hormones and Their Functions

2.8K
Hormones, the biochemical messengers produced by endocrine glands, are pivotal in regulating bodily functions and maintaining homeostasis. Each hormone's balance is crucial; imbalances can lead to significant physiological disruptions. Major hormones include oxytocin, cortisol, epinephrine, estrogen, testosterone, thyroxine, growth hormone, insulin, and glucagon.
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
2.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

General vs spinal anesthesia in transvaginal hysterectomy with anterior and posterior repair with pelvic organ prolapse patients: Retrospective cohort study.

Medicine·2026
Same author

Recurrence Rate of Pelvic Organ Prolapse after Total Vaginal Hysterectomy with Anteroposterior Colporrhaphy.

Chonnam medical journal·2026
Same author

The 2025 Menopausal Hormone Therapy Guidelines - Korean Society of Menopause.

Journal of menopausal medicine·2025
Same author

Erratum to: Corrigendum: 2023 Korean Society of Menopause - Osteoporosis Guidelines Part I.

Journal of menopausal medicine·2025
Same author

The 2024 Guidelines for Osteoporosis - Korean Society of Menopause: Part II.

Journal of menopausal medicine·2024
Same author

Corrigendum: 2023 Korean Society of Menopause - Osteoporosis Guidelines Part I.

Journal of menopausal medicine·2024

Related Experiment Video

Updated: Mar 26, 2026

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies
06:24

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies

Published on: January 10, 2025

1.7K

Thyroid dysfunction and subfertility.

Moon Kyoung Cho1

  • 1Department of Obstetrics and Gynecology, Chonnam National University Medical School, Gwangju, Korea.

Clinical and Experimental Reproductive Medicine
|January 28, 2016
PubMed
Summary
This summary is machine-generated.

Thyroid dysfunctions are common in women of reproductive age and can cause subfertility. Early diagnosis and management of thyroid issues, including subclinical hypothyroidism (SCH) and thyroid autoimmunity (TAI), are crucial for fertility.

Keywords:
AutoimmunityHypothyroidismInfertilityThyroid hormones

More Related Videos

Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model
04:14

Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model

Published on: October 6, 2023

1.4K
Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
04:39

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

Published on: March 17, 2023

2.6K

Related Experiment Videos

Last Updated: Mar 26, 2026

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies
06:24

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies

Published on: January 10, 2025

1.7K
Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model
04:14

Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model

Published on: October 6, 2023

1.4K
Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
04:39

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

Published on: March 17, 2023

2.6K

Area of Science:

  • Reproductive endocrinology and thyroidology.

Background:

  • Thyroid hormones are essential for cellular function and reproduction.
  • Thyroid dysfunctions are prevalent in women of reproductive age, impacting fertility through hormonal imbalances and anovulatory cycles.
  • Subclinical hypothyroidism (SCH) and thyroid autoimmunity (TAI) can be asymptomatic yet contribute to subfertility.

Purpose of the Study:

  • To review the intricate relationship between thyroid dysfunction and female subfertility.
  • To outline appropriate diagnostic strategies and management protocols for thyroid disorders in subfertile women.

Main Methods:

  • This review synthesizes current literature on thyroid function, autoimmunity, and reproductive health.
  • It examines the impact of thyroid dysfunctions on fertility parameters and treatment outcomes.
  • The review also considers the effects of assisted reproductive technologies, like controlled ovarian hyperstimulation, on thyroid function.

Main Results:

  • Thyroid dysfunctions, including SCH and TAI, are significant contributors to subfertility in women.
  • These conditions can lead to anovulation, hyperprolactinemia, and sex hormone imbalances.
  • Controlled ovarian hyperstimulation can notably affect thyroid function, especially in women with TAI.

Conclusions:

  • Undiagnosed or untreated thyroid disease is a treatable cause of subfertility.
  • Comprehensive evaluation and management of thyroid health are vital for optimizing reproductive outcomes in women experiencing fertility challenges.
  • Prompt diagnosis and treatment of SCH and TAI can improve fertility rates.