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Published on: November 20, 2015
Morbidity and Mortality Pattern in Late Preterm Infants at a Tertiary Care Hospital in Jammu & Kashmir, Northern
Ghulam Nabi Rather1, Muzafar Jan2, Wasim Rafiq3
1Registrar, Department of Pediatrics, Government Medical College , Srinagar, J&K, India .
Insights
Late preterm infants (34-36 weeks) face higher risks of neonatal morbidity and mortality compared to full-term infants. This study highlights increased rates of respiratory issues, jaundice, hypoglycemia, and sepsis in this vulnerable group.
Area of Science:
- Neonatal Medicine
- Pediatrics
- Public Health
Background:
- Late preterm infants (34-36 6/7 weeks) exhibit higher morbidity and mortality rates than term infants due to physiological and metabolic immaturity.
- Despite similar weight and size, late preterm infants are at increased risk for adverse neonatal outcomes.
Purpose of the Study:
- To determine the incidence of late preterm births.
- To investigate early neonatal morbidity and mortality within the first seven days of life in late preterm infants.
Main Methods:
- A prospective, hospital-based study conducted from April 2012 to March 2013.
- Inclusion of 4100 neonates in the study population.
- Data collected from G.B. Pant General Hospital and associated hospitals in Srinagar.
Main Results:
- The incidence of late preterm neonates was 11.58%.
- Late preterm infants showed significantly higher risks for overall morbidity (76.8%) including respiratory morbidity, need for mechanical ventilation, jaundice, hypoglycemia, and sepsis compared to term infants (28.3%).
- Early neonatal mortality rate in late preterm infants was 2.5% (25/1000 live births).
Conclusions:
- Late preterm infants face substantially higher risks of neonatal morbidity, including respiratory distress, jaundice, hypoglycemia, and sepsis, compared to term infants.
- The study confirms a higher early neonatal mortality rate in late preterm infants.
- These findings underscore the need for targeted monitoring and care for late preterm neonates.
Introduction:
The morbidity and mortality pattern in late preterm infants is higher than term infants (gestational age ≥ 37weeks). The main reason behind that is the relative physiologic and metabolic immaturity, though there is no significant difference in the weight or the size of the two groups.
Aim:
The present study was undertaken to study the incidence, early neonatal morbidity and mortality (within first 7 days of life) in late preterm infants (34 - 36 6/7 weeks).
Materials And Methods:
It was a hospital based prospective study conducted from April 2012 to March 2013. The study was conducted in the Department of Paediatrics and Neonatology at G.B. Pant General Hospital and Department of Gynaecology and Obstetrics L.D hospital and G.B. pant general hospital, (associated hospitals of Government Medical College, Srinagar).
Results:
A total of 4100 neonates were included in the study. Incidence of late preterm neonates was 11.58 %. Three hundred sixty five (76.8%) of late preterm and 965 (28.3%) of term infants had at least one of the predefined neonatal conditions. Late preterm infants were at significantly higher risk for overall morbidity due to any cause (p<0.0001), respiratory morbidity (p<0.0001), mechanical ventilation (p=0.0002), jaundice (p<0.0001), hypoglycaemia (p<0.0001), and sepsis (p<0.0001) Perinatal asphyxia (p= 0.186). Early neonatal mortality in late preterm neonates was 2.5% or 25/1000 live births.
Conclusion:
Compared with term infants, late preterm infants are at high risk for overall morbidity, respiratory morbidity, and need of mechanical ventilation, jaundice, hypoglycaemia & sepsis. They also have a higher mortality as compared to term neonates.
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