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[THE RISK FACTORS OF THE DIALYSIS PERITONITIS (THREE-YEARS PROSPECTIVE INVESTIGATION)].

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    Dialysis peritonitis, an infection during peritoneal dialysis for chronic kidney disease, occurred in 57.5% of patients. Key risk factors identified include obesity, high serum albumin, constipation, and catheter site injection.

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    Area of Science:

    • Nephrology
    • Infectious Diseases
    • Public Health

    Context:

    • Chronic renal disease patients undergoing peritoneal dialysis (PD) are susceptible to dialysis peritonitis.
    • A prospective study was conducted at Kyiv City Oleksandrivska Clinical Hospital from 2007-2010.
    • PD is a crucial renal replacement therapy for end-stage renal disease.

    Purpose:

    • To identify and analyze the risk factors associated with the occurrence of dialysis peritonitis in patients on PD.
    • To determine the incidence and cumulative rate of dialysis peritonitis in a cohort of patients.
    • To assess the impact of dialysis peritonitis on the continuation of PD therapy.

    Summary:

    • The study investigated 73 patients with chronic renal disease undergoing PD, with 57.5% experiencing a first episode of dialysis peritonitis.
    • The cumulative incidence of dialysis peritonitis reached 67.7%, leading to the discontinuation of PD in 19.2% of patients.
    • Identified risk factors for dialysis peritonitis include obesity, elevated serum albumin levels, constipation, and prior catheter exit site injection.

    Impact:

    • Findings highlight significant risk factors that can be targeted for preventive strategies in PD patients.
    • Understanding these risk factors can help clinicians optimize patient care and reduce peritonitis-related complications.
    • This research contributes to improving the safety and efficacy of peritoneal dialysis as a renal replacement therapy.