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PECULIARITIES OF THE COURSE OF THE UPPER ALIMENTARY TRACT DISEASES IN CHILDREN WITH BRONCHOOBSTRUCTIVE SYNDROME
Insights
Gastroesophageal reflux disease (GERD) is frequently associated with bronchoobstructive syndrome (BOS) in children, impacting respiratory conditions like asthma. Tailored anti-reflux treatments improve outcomes for pediatric patients with these combined conditions.
Area of Science:
- Pediatric Pulmonology
- Gastroenterology
- Internal Medicine
Background:
- Bronchoobstructive syndrome (BOS) in children often co-occurs with gastroesophageal reflux disease (GERD).
- This association complicates the management of respiratory conditions such as bronchial asthma (BA), pneumonia, and recurrent obstructive bronchitis.
- Understanding the interplay between GERD and pediatric respiratory diseases is crucial for effective treatment strategies.
Purpose of the Study:
- To enhance treatment tactics for bronchoobstructive syndrome (BOS) in children with co-existing gastroesophageal reflux disease (GERD).
- To investigate the prevalence and characteristics of GERD in children with various respiratory conditions.
- To evaluate the efficacy of individualized anti-reflux programs in managing these complex cases.
Main Methods:
- A study involving 180 children (aged 6-16) diagnosed with respiratory diseases and GERD symptoms.
- Included patients with bronchial asthma (BA), acute pneumonia, and recurrent obstructive bronchitis.
- Utilized diagnostic tools such as pH-metry, esophagofibrogastroduodenoscopy (EFGDS), spirometry, and gastrointestinal ultrasound (USI).
Main Results:
- GERD was associated with respiratory diseases presenting BOS in 43.9% of cases.
- GERD was significantly more frequent in boys with severe BA and in girls with lengthy pneumonia.
- Individualized anti-reflux programs integrated into complex therapy reduced exacerbations and hospitalizations, improving quality of life for pediatric patients.
Conclusions:
- GERD is a significant comorbidity in children with bronchoobstructive syndrome, particularly in those with bronchial asthma.
- Early identification and management of GERD are essential for optimizing treatment outcomes in pediatric respiratory illnesses.
- Integrated anti-reflux strategies represent a promising approach to improving the management and quality of life for children with associated BOS and GERD.
Unlabelled:
The aim of the study was to improve the tactics of treatment of bronchoobstructive syndrome (BOS) in associative course with gastroesophageal reflux disease (GERD) in children.
Materials And Methods:
180 children aged 6-16 with diseases of the respiratory organs with BOS and GERD symptoms were examined: 85 of them--with bronchial asthma (BA), 34--with an acute course of pneumonia, 29--with recurrent obstructive bronchitis. Comparison groups were composed of 93 children, the number of practically healthy children (the control group) was 28 persons. The analysis of risk factors of associative pathology development, roentgenographic study, investigation of the function of external respiration (FER) (peak flowmetry, spirometry), intracavitary pH-metry, esophagofibrogastroduodenoscopy (EFGDS) and ultrasonic investigation (USI) of the organs of the gastro-intestinal tract (GIT) were carried out.
Results:
Diseases of the respiratory organs with BOS in the groups of the patients under investigation in 43.9% of cases on an average associated with GERD. In a severe course of bronchial asthma GERD was detected 3,4 times more frequently in the boys, while in a lengthy course of pneumonia with BOS--1,9 times more frequently in the girls. Chronic gastritis (ChG) and chronic gastroduodenitis (ChGD) in BA were revealed in 40.6% of the patients, in pneumonia--in 45.7%, in recurrent bronchitis--in 33.3% of the patients. Peculiarities of pre-morbid background of BA and GERD associative course were exhibited by gestosis, threat of abortion, intrauterine hypoxia of the fetus, social troubles of the family. Manifestations of BA in children in 36% of cases were observed 6-12 months after the onset of GERD. The designed individual anti-reflux programs in complex therapy of respiratory organs' diseases with BOS associated with GERD reduce the frequency of exacerbations and hospitalizations of patients with BA, improve their life quality.
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