Related Experiment Video
Updated: Mar 26, 2026

Method of Studying Palatal Fusion using Static Organ Culture
Published on: September 19, 2015
[Cleft lip and palate--risk factors, prenatal diagnosis, and health consequences]
Insights
Cleft lip and/or palate are congenital malformations influenced by genetic and environmental factors. This study examines environmental risks, prenatal diagnosis, and health outcomes for these conditions.
Area of Science:
- Medical Genetics
- Developmental Biology
- Public Health
Abstract:
Cleft lip and/or palate is a diverse and important group of congenital malformations. The incidence is estimated at 1 in 600-1000 births worldwide. In Poland, there are 2-3 cases noted per 1000 live births. The process of the formation of a correctly developed lip and palate can be impaired by a variety of factors, including the extremely important role of the interaction between genetic and environmental factors (smoking, alcohol consumption, medication use, and exposure to certain chemicals). This study focuses on environmental risk factors, prenatal diagnosis, and health consequences of cleft lip and palate.
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