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Acute gluteal abscesses: injectable chloroquine as a cause
The Journal of Tropical Medicine and Hygiene
|October 1, 1989
Summary
Acute gluteal abscesses are frequently caused by intramuscular injections, particularly chloroquine antimalarial drugs. This study highlights the need for improved injection practices to prevent these common pyogenic injection abscesses.
Area of Science:
- Medicine
- Infectious Diseases
- Public Health
Background:
- Gluteal abscesses are a common complication of intramuscular injections.
- Chloroquine, an antimalarial drug, is frequently implicated in the development of these abscesses.
Purpose of the Study:
- To investigate the causes and characteristics of acute gluteal abscesses.
- To identify risk factors associated with the development of injection-related gluteal abscesses.
Main Methods:
- Retrospective study of 107 patients admitted with acute gluteal abscesses.
- Analysis of patient records to determine the cause, drug administered, injection technique, and bacteriology.
Main Results:
- 85% of abscesses resulted from intramuscular injections, with 66% linked to chloroquine.
- Disposable syringes were used in 70% of cases; injections were administered by nurses in 55%.
- Staphylococcus aureus was the most common pathogen (54%) in cultured abscesses.
Conclusions:
- Pyogenic injection abscesses are a significant complication of intramuscular chloroquine injections in the gluteal region.
- Adherence to sterile injection techniques and appropriate drug administration are crucial for prevention.