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Association between sleeping difficulty and type 2 diabetes in women
Yanping Li1, Xiang Gao2, John W Winkelman3,4
1Department of Nutrition, Harvard T. H. Chan School of Public Health, 665 Huntington Ave, Boston, MA, 02115, USA.
Diabetologia
|January 29, 2016
Summary
Sleeping difficulty is linked to a higher risk of type 2 diabetes. This association is stronger when combined with other sleep issues, emphasizing sleep disturbance
Area of Science:
- Epidemiology
- Sleep Medicine
- Endocrinology
Background:
- Prior studies suggest a link between sleeping difficulty and type 2 diabetes.
- The independence of this association from health behaviors and other sleep disorders requires clarification.
Purpose of the Study:
- To investigate the association between sleeping difficulty and incident type 2 diabetes.
- To determine if this association is independent of lifestyle factors, cardiovascular risk factors, and other sleep disorders.
Main Methods:
- Analysis of data from 133,353 women in the Nurses' Health Study (NHS) and NHSII.
- Assessment of sleeping difficulty (difficulty falling/staying asleep) at baseline.
- Follow-up for incident type 2 diabetes cases over 10 years.
Main Results:
- Sleeping difficulty was associated with a 45% increased risk of type 2 diabetes (HR 1.45).
- This risk decreased to 22% after adjusting for hypertension, depression, and BMI (HR 1.22).
- Combined sleep issues (difficulty, snoring, short duration, sleep apnea/shift work) increased type 2 diabetes likelihood over fourfold (HR 4.17).
Conclusions:
- Sleeping difficulty is significantly associated with type 2 diabetes.
- Hypertension, BMI, and depression partially explain this link.
- The association is amplified by co-occurring sleep disorders, highlighting sleep disturbance's role in type 2 diabetes development and prevention.
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