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Updated: Mar 26, 2026

Induced Pluripotent Stem Cell Generation from Blood Cells Using Sendai Virus and Centrifugation
Published on: December 21, 2016
Effect of Induced Pluripotent Stem Cell Technology in Blood Banking
Daniele Focosi1, Mauro Pistello2
1North-Western Tuscany Blood Bank, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.
Abstract:
Population aging has imposed cost-effective alternatives to blood donations. Artificial blood is still at the preliminary stages of development, and the need for viable cells seems unsurmountable. Because large numbers of viable cells must be promptly available for clinical use, stem cell technologies, expansion, and banking represent ideal tools to ensure a regular supply. Provided key donors can be identified, induced pluripotent stem cell (iPSC) technology could pave the way to a new era in transfusion medicine, just as it is already doing in many other fields of medicine. The present review summarizes the current state of research on iPSC technology in the field of blood banking, highlighting hurdles, and promises.
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