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Isolated Supratentorial Intraventricular Recurrence of Medulloblastoma
Kingsley O Abode-Iyamah1, Nolan Winslow1, Oliver Flouty1
1Department of Neurosurgery, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Abstract:
Medulloblastoma is a common pediatric tumor typically diagnosed before the age of fifteen. Initial therapy includes surgical resection and radiation of the entire neuro-axis. Recurrence is common and typically occurs within 2 years of initial diagnosis. Those fitting Collin's Law is considered tumor-free. We report a case of single supratentorial recurrence 13 years after initial diagnosis. Here we present a 22 year old male presenting 13 years after initial diagnosis with isolated septum pellucidum recurrence. He underwent complete resection of the tumor. Medulloblastoma is a common in the pediatric population. Late recurrence to the ventricular system is uncommon. Long term follow-up is recommended in these patients.
Insights
Late recurrence of medulloblastoma (a common pediatric brain tumor) can occur years after initial treatment. This case highlights a rare, isolated recurrence 13 years post-diagnosis, emphasizing the need for long-term patient monitoring.
Area of Science:
- Pediatric Oncology
- Neuro-Oncology
- Tumor Recurrence
Background:
- Medulloblastoma is a frequent pediatric brain tumor, typically treated with surgery and neuro-axis radiation.
- Recurrence commonly happens within two years, with tumor-free status often defined by Collin's Law.
- Long-term surveillance is crucial for patients with medulloblastoma.
Observation:
- A 22-year-old male presented with an isolated supratentorial recurrence of medulloblastoma.
- The recurrence was located in the septum pellucidum, 13 years after his initial diagnosis and treatment.
- The patient underwent complete surgical resection of the recurrent tumor.
Findings:
- Late, isolated recurrences of medulloblastoma to the ventricular system are uncommon.
- This case demonstrates a recurrence significantly beyond the typical 2-year window.
Implications:
- The findings suggest that extended follow-up protocols may be warranted for medulloblastoma survivors.
- This case underscores the importance of vigilance for late-onset tumor recurrence in pediatric brain tumor patients.
- Further research into the mechanisms of late medulloblastoma recurrence is needed.
