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In vivo burn diagnosis by camera-phone diffuse reflectance laser speckle detection
1Biomedical Engineering Department, Ben-Gurion University of the Negev, 1 Ben Gurion Blvd, POB 653, Be'er-Sheva 8410501, Israel.
Biomedical Optics Express
|January 29, 2016
Summary
This study introduces a novel point illumination method for diagnosing burns using diffuse reflectance laser speckle. This technique, utilizing a camera-phone, can distinguish partial-thickness burns and monitor healing in vivo.
Area of Science:
- Biomedical optics
- Medical imaging
- Dermatology
Background:
- Conventional laser speckle imaging for burn diagnosis uses widefield illumination.
- Analysis of speckle contrast in time-integrated patterns assesses burn severity.
- Existing systems often require specialized, high-grade cameras.
Purpose of the Study:
- To develop and validate a point illumination diffuse reflectance laser speckle method for burn diagnosis.
- To assess the system's ability to differentiate burn types and monitor healing.
- To demonstrate the feasibility of using a camera-phone for burn diagnosis.
Main Methods:
- Utilized point illumination to generate diffuse reflectance laser speckle patterns from burns.
- Examined spatiotemporal fluctuations in time-integrated patterns along the radial direction.
- Tested the system in a porcine model in vivo within 24 hours post-burn.
Main Results:
- Successfully distinguished partial-thickness burns in vivo using the point illumination method.
- Findings suggest potential for monitoring burn healing over time.
- Demonstrated burn diagnosis capability with a simple camera-phone imager.
Conclusions:
- Point illumination diffuse reflectance laser speckle offers a novel approach for burn diagnosis.
- The camera-phone based system shows promise for accessible and portable burn assessment.
- This method could aid in early burn severity determination and healing monitoring.
