Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Development of the Lymphatic System

Development of the Lymphatic System

The development of lymphatic tissues and vessels in embryonic life begins around the fifth week. These structures originate from the mesoderm layer, with lymph sacs emerging from developing veins.
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...

Detailed Structure and Function of Lymph Nodes

Detailed Structure and Function of Lymph Nodes

Lymph nodes are bean-shaped structures that cluster along the lymphatic vessels in the inguinal, axillary, and cervical regions. Each node is divided into compartments by a capsule that extends trabeculae inward.
From a histological perspective, lymph nodes can be split into two main areas: the superficial cortex and the deep medulla. The outer cortex is populated by dendritic cells, macrophages, and B lymphocytes, which are densely packed into follicles. When these B-lymphocytes are presented...

Lymphatic Vessels and Lymph Transport

Lymphatic Vessels and Lymph Transport

Lymphatic vessels, known as lymphatics, are crucial in transporting lymph from peripheral tissues to our venous system. This process begins with lymph entering through tiny capillaries that branch through tissues. These capillaries have unique features such as larger diameters, thinner walls, and a distinctive one-way valve system formed by overlapping endothelial cells.
This one-way system allows fluids, solutes, and even pathogens to enter but prevents their return to the intercellular...

Lymphoid Cells and Tissues

Lymphoid Cells and Tissues

Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes.
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...

Secondary Lymphoid Organs

Secondary Lymphoid Organs

Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...

Veins of Head and Neck

Veins of Head and Neck

The blood drainage from the head and neck is primarily managed by three pairs of veins: the external jugular, internal jugular, and vertebral veins. The external jugular veins drain superficial scalp and face structures, passing over the sternocleidomastoid muscles to empty into the subclavian veins.
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A simple clinical risk score can predict frailty in HNSCC patients.

Cancer treatment and research communications·2026

Same author

Laryngo- rhino- otologie·2026

Same author

Laryngo- rhino- otologie·2026

Same author

Laryngo- rhino- otologie·2026

Same author

Laryngo- rhino- otologie·2026

Same author

Laryngo- rhino- otologie·2025

Search research articles

Related Experiment Video

Updated: Mar 26, 2026

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Published on: May 1, 2015

[Lymphatic malformations in the head and neck area].

S Wiegand¹, J A Werner²

¹Klinik für Hals-Nasen-Ohrenheilkunde, Kopf- und Halschirurgie, Universitätsklinikum Gießen und Marburg (UKGM), Standort Marburg, Baldingerstraße, 35037, Marburg, Deutschland. swiegand@med.uni-marburg.de.

|January 29, 2016

Summary

Lymphatic malformations are congenital conditions affecting the lymphatic system, primarily in the head and neck. Treatment for these malformations, especially microcystic types, involves surgery, laser therapy, sclerotherapy, and drug therapies.

Keywords:

Abnormality Lymphangioma Sclerotherapy Surgery Vascular malformations

More Related Videos

Cervical Lymph Duct-Cannulated Rat Model for Assessing Lymphatic Transport from the Head and Brain

Cervical Lymph Duct-Cannulated Rat Model for Assessing Lymphatic Transport from the Head and Brain

Published on: March 10, 2026

A Murine Tail Lymphedema Model

A Murine Tail Lymphedema Model

Published on: February 10, 2021

Related Experiment Videos

Last Updated: Mar 26, 2026

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Published on: May 1, 2015

Cervical Lymph Duct-Cannulated Rat Model for Assessing Lymphatic Transport from the Head and Brain

Cervical Lymph Duct-Cannulated Rat Model for Assessing Lymphatic Transport from the Head and Brain

Published on: March 10, 2026

A Murine Tail Lymphedema Model

A Murine Tail Lymphedema Model

Published on: February 10, 2021

Area of Science:

Vascular Anomalies
Pediatric Surgery
Congenital Malformations

Background:

Lymphatic malformations (LMs) are congenital anomalies of the lymphatic system.
They predominantly occur in the head and neck region.
LMs grow proportionally with the patient.

Purpose of the Study:

To review the classification and therapeutic approaches for lymphatic malformations.
To highlight the challenges in treating microcystic lymphatic malformations due to their infiltrative nature.

Main Methods:

Classification based on LM morphology: macrocystic, microcystic, and mixed.
Overview of current therapeutic strategies.

Main Results:

Microcystic lymphatic malformations present significant treatment challenges.
Diverse therapeutic options are available, including surgery, laser, sclerotherapy, and systemic drugs.

Conclusions:

Effective management of lymphatic malformations requires understanding their morphology and growth patterns.
A multimodal therapeutic approach is often necessary for optimal outcomes, particularly for infiltrative microcystic LMs.