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ANKRD53 interacts with DDA3 and regulates chromosome integrity during mitosis

Seul Kim1, Chang-Young Jang1

  • 1Research Center for Cell Fate Control, College of Pharmacy, Sookmyung Women's University, Seoul 140-742, Republic of Korea.

Biochemical and Biophysical Research Communications
|January 29, 2016
PubMed
Summary

ANKRD53, a novel DDA3-interacting protein, regulates spindle dynamics during mitosis. Depletion of ANKRD53 delays mitotic progression and impairs chromosome segregation, highlighting its role in cell division.

Keywords:
ANKRD53Chromosome movementDDA3Mitotic spindleSpindle dynamics

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