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Murine Full-thickness Skin Transplantation
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Infection Prevention in Transplantation.

Steven A Pergam1,2,3,4

  • 1Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. North, E4-100, Seattle, WA, 98109, USA. spergam@fredhutch.org.

Current Infectious Disease Reports
|January 29, 2016
PubMed
Summary

Hematopoietic cell and solid organ transplant patient numbers are rising, increasing infection risks. Updated strategies are crucial for preventing healthcare-associated infections and antimicrobial-resistant pathogens in transplant recipients.

Keywords:
Clostridium difficileFilamentous moldFungusHand hygieneInfection controlInfection preventionMRSAMeaslesRespiratory virusesScreeningTransplantVREVaccines

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Area of Science:

  • Transplantation Medicine
  • Infectious Diseases
  • Healthcare-Associated Infections

Background:

  • Increasing numbers of hematopoietic cell and solid organ transplant procedures annually.
  • Significant improvements in transplant survival due to advancements in procedures and immunosuppression.
  • Infections remain a primary cause of morbidity and mortality in transplant recipients.

Purpose of the Study:

  • To provide an update on recent data regarding the prevention of major healthcare-associated infections specific to transplantation.
  • To review the emergence and impact of antimicrobial-resistant infections in transplant populations.
  • To discuss updated strategies for identifying and preventing pathogen transmission in transplant recipients.

Main Methods:

  • Review of recent scientific literature and clinical data on infection prevention in transplantation.
  • Analysis of emerging trends in antimicrobial resistance relevant to transplant patients.
  • Discussion of current and novel strategies for pathogen identification and transmission control.

Main Results:

  • Infection prevention strategies are critical for reducing complications and improving outcomes in transplant centers.
  • Antimicrobial resistance poses a growing threat to transplant recipients.
  • Updated identification and prevention protocols are essential for managing infections in this high-risk group.

Conclusions:

  • Effective infection prevention is paramount for managing the increasing population of transplant recipients.
  • Addressing antimicrobial resistance requires updated and proactive management strategies.
  • Continuous vigilance and implementation of evidence-based practices are necessary to safeguard transplant patient health.