Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Obesity01:24

Obesity

1.5K
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
1.5K
Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

335
In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
335
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

345
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
345
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution01:25

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

374
Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
374
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion01:20

Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion

281
Drug metabolism, a critical process in the liver, involves two primary phases: Phase I reactions and Phase II conjugation. Obesity introduces significant alterations in this metabolic process, primarily due to fatty infiltration of the liver, leading to conditions such as nonalcoholic fatty liver disease (NAFLD). This condition can modify the activities of both Phase I and II enzymes, impacting how drugs are metabolized in obese patients.Phase I metabolism sees variable effects across...
281
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

335
Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
335

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Antihyperglycemic treatment of type 2 diabetes mellitus (Update 2026)].

Wiener klinische Wochenschrift·2026
Same author

[Diagnostics and treatment of type 1 diabetes mellitus (Update 2026)].

Wiener klinische Wochenschrift·2026
Same author

[Management of hyperglycemia in pregnancy (Update 2026)].

Wiener klinische Wochenschrift·2026
Same author

[Geriatric aspects of diabetes mellitus (Update 2026)].

Wiener klinische Wochenschrift·2026
Same author

[Sex and gender-specific aspects in prediabetes and diabetes mellitus - Clinical recommendations (Update 2026)].

Wiener klinische Wochenschrift·2026
Same author

Effects of family history and sex on diabetes-related outcome in type 2 diabetes - Analysis from the tyrolean diabetes registry.

PloS one·2025
Same journal

Regenerative therapies in rehabilitation with interfaces with occupational medicine, geriatrics, and oncology: the example of extracorporeal shock wave therapy.

Wiener medizinische Wochenschrift (1946)·2026
Same journal

Cerebral toxoplasmosis in patients with peripheral B-cell lymphoma : A case series and a literature review.

Wiener medizinische Wochenschrift (1946)·2026
Same journal

Post-pandemic rebound of rotavirus and adenovirus in pediatric gastroenteritis: a 6-year antigen-based surveillance study from Turkey.

Wiener medizinische Wochenschrift (1946)·2026
Same journal

Neuroaxis involvement in Chikungunya virus infection: a retrospective case series.

Wiener medizinische Wochenschrift (1946)·2026
Same journal

A complicated case of a spinal Scedosporium apiospermum infection with a favorable outcome-case report.

Wiener medizinische Wochenschrift (1946)·2026
Same journal

Wiener medizinische Wochenschrift (1946)·2026
See all related articles

Related Experiment Video

Updated: Mar 26, 2026

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People
12:59

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People

Published on: July 5, 2017

13.3K

[Obesity in elderly].

Monika Lechleitner1

  • 1Landeskrankenhaus Hochzirl-Natters, 6170, Zirl, Österreich. monika.lechleitner@tirol-kliniken.at.

Wiener Medizinische Wochenschrift (1946)
|January 29, 2016
PubMed
Summary
This summary is machine-generated.

Obesity is rising in older adults, increasing risks for health issues. Tailored nutrition and exercise can improve quality of life and manage comorbidities in the elderly.

Keywords:
ElderlyMalnutritionObesity

More Related Videos

Multidisciplinary Approach to Obesity Management: A Case Report
05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

1.4K
Assessment of Child Anthropometry in a Large Epidemiologic Study
09:36

Assessment of Child Anthropometry in a Large Epidemiologic Study

Published on: February 2, 2017

28.0K

Related Experiment Videos

Last Updated: Mar 26, 2026

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People
12:59

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People

Published on: July 5, 2017

13.3K
Multidisciplinary Approach to Obesity Management: A Case Report
05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

1.4K
Assessment of Child Anthropometry in a Large Epidemiologic Study
09:36

Assessment of Child Anthropometry in a Large Epidemiologic Study

Published on: February 2, 2017

28.0K

Area of Science:

  • Gerontology
  • Public Health
  • Nutritional Science

Background:

  • Rising obesity prevalence in the elderly population presents significant health challenges.
  • European Euronut-Seneca study reported obesity rates of 12-41% in elderly women and 8-24% in men.
  • Obesity in older adults is linked to cardiometabolic risk, joint diseases, and reduced physical function.

Purpose of the Study:

  • To explore the complexities of obesity in the elderly, including the obesity paradox.
  • To highlight the association of sarcopenic obesity with poorer health outcomes.
  • To emphasize the need for integrated preventive and therapeutic strategies.

Main Methods:

  • Analysis of data from the European Euronut-Seneca study.
  • Review of literature on obesity, cardiometabolic risk, and functional decline in older adults.
  • Consideration of malnutrition risks in elderly populations.

Main Results:

  • Obesity prevalence varies significantly between elderly men and women.
  • The 'obesity paradox' presents complex prognostic considerations for certain diseases.
  • Sarcopenic obesity is identified as a condition with the worst prognosis.

Conclusions:

  • Preventive and therapeutic approaches must address the heightened risk of malnutrition in the elderly.
  • Individually tailored nutritional recommendations combined with physical exercise are beneficial.
  • Integrated strategies can improve the prognosis of comorbidities and enhance the quality of life for older adults.