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SEPSIS KILLS: early intervention saves lives
Anthony R Burrell1, Mary-Louise McLaws2, Mary Fullick3
1Clinical Excellence Commission, Sydney, NSW m.mclaws@unsw.edu.au,rosemary.sullivan@health.nsw.gov.au.
The Medical Journal of Australia
|January 29, 2016
Summary
The SEPSIS KILLS program improved sepsis care in NSW hospitals, increasing timely interventions and reducing overall mortality. This quality improvement initiative focused on early recognition and treatment, particularly in ward settings.
Area of Science:
- Public Health
- Quality Improvement Science
- Emergency Medicine
Background:
- Sepsis is a life-threatening condition requiring prompt recognition and treatment.
- Early intervention is crucial for improving patient outcomes and reducing mortality.
- Implementing standardized protocols across a large healthcare system can enhance sepsis management.
Purpose of the Study:
- To implement and evaluate a statewide program for the early recognition and treatment of sepsis in New South Wales (NSW), Australia.
- To assess the impact of the SEPSIS KILLS program on key performance indicators related to sepsis care.
- To improve patient outcomes, including mortality rates and length of hospital stay, through a structured quality improvement initiative.
Main Methods:
- A statewide quality improvement program, SEPSIS KILLS, was implemented across 97 emergency departments in NSW hospitals.
- The program promoted interventions within 60 minutes of sepsis recognition, including blood cultures, lactate measurement, intravenous antibiotics, and fluid resuscitation.
- Data from 13,567 patients were analyzed to assess changes in process measures and patient outcomes over time.
Main Results:
- The proportion of patients receiving intravenous antibiotics within 60 minutes increased from 29.3% to 52.2% (P < 0.001).
- Timely fluid resuscitation also improved, with the percentage of patients receiving a second litre within 60 minutes rising from 10.6% to 27.5% (P < 0.001).
- Overall mortality decreased from 19.3% to 14.1% (P < 0.0001), with significant reductions in intensive care unit (ICU) time and total length of stay.
Conclusions:
- The SEPSIS KILLS program successfully improved the process of care for sepsis patients in NSW hospitals.
- The initiative demonstrated the effectiveness of a focused quality improvement program in enhancing sepsis recognition and management.
- The program highlighted the importance of interventions in ward settings for improving sepsis outcomes.
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