Left ventricular volumes by echocardiography in chronic aortic and mitral regurgitations

Odd Bech-Hanssen1,2,3,4, Christian Lars Polte1,3, Kerstin M Lagerstrand5,6

  • 1a Department of Cardiology , Sahlgrenska Academy at the University of Gothenburg , Gothenburg , Sweden ;

Insights

Echocardiography can help diagnose severe aortic or mitral regurgitation by measuring left ventricular (LV) volumes. New cut-off values for LV end-diastolic volume index are proposed for accurate assessment.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Echocardiography

Background:

  • Defining cut-off values for left ventricular (LV) dimensions in severe valve regurgitation is crucial.
  • Current echocardiographic methods lack precise criteria for severe chronic aortic regurgitation (AR) and mitral regurgitation (MR).

Purpose of the Study:

  • To establish echocardiographic cut-off values for LV dimensions that indicate severe chronic AR or MR.
  • To validate these values against cardiovascular magnetic resonance (CMR) findings.

Main Methods:

  • Eighty-three patients with moderate to severe AR or MR underwent 2D echocardiography (2DE), real-time 3D echocardiography (RT3DE), and CMR.
  • Hemodynamic significance was confirmed by reduced end-diastolic volume (EDV) and symptom relief post-surgery.

Main Results:

  • Strong correlations were found between CMR-derived EDV and echocardiographic EDV (R=0.95 for 2DE, R=0.91 for RT3DE).
  • Specific EDV index cut-offs were identified: >87/104 ml/m² for AR and >69/87 ml/m² for MR using 2DE/RT3DE.
  • LV linear dimensions were not effective in identifying severe regurgitation.

Conclusions:

  • Echocardiographic LV volumes can aid in diagnosing severe chronic regurgitation.
  • These established cut-off values provide valuable diagnostic support.
  • Consideration of other causes for LV enlargement is important in clinical practice.

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