Related Experiment Videos
Cellular localization of heat shock gene expression in rabbit cerebellum by in situ hybridization with
1Department of Zoology, University of Toronto, West Hill, Ontario, Canada.
Neurochemical Research
|August 1, 1989
Abstract:
The major cell types in rabbit cerebellum which engage in the expression of a heat shock gene (hsp70) after hyperthermia were identified. This required in situ hybridization on thin sections derived from plastic-embedded tissue. All classes of cerebellar neurons which were examined (Purkinje, granule, and stellate cells) responded by induction of hsp70 mRNA within 1 hr after hyperthermia. Prominent induction of hsp70 mRNA was also observed in oligodendroglia in the deep white matter.