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Cardial leiomyosarcoma with multiple lesions involved: a case report
Yan Lv1, Xin Pang2, Qingfu Zhang3
1Department of Cardiovascular, The First Affiliated Hospital of China Medical University Shenyang 110001, People's Republic of China.
International Journal of Clinical and Experimental Pathology
|January 30, 2016
Summary
Cardiac leiomyosarcoma is a rare vascular tumor with a poor prognosis. Surgical resection is the primary treatment, and combining it with chemotherapy may improve survival outcomes for patients.
Area of Science:
- Cardiovascular Pathology
- Surgical Oncology
- Vascular Tumors
Background:
- Cardiac leiomyosarcoma is an exceptionally rare malignancy with a historically poor prognosis.
- Median survival for patients with heart involvement is approximately six months.
Observation:
- A case of a 43-year-old female presenting with palpitations and dyspnea.
- Diagnosis revealed extensive vascular leiomyosarcoma involving the iliac veins, inferior vena cava, right atrium, and pulmonary arteries.
- The patient survived for 12 months post-surgery.
Findings:
- Surgical resection is the cornerstone of treatment for cardiac leiomyosarcoma.
- A review of 30 cases indicates that multimodal therapy, including surgery and chemotherapy, may enhance survival.
Implications:
- Aggressive surgical management is crucial for managing cardiac leiomyosarcoma.
- Further research into neoadjuvant and adjuvant therapies is warranted to improve patient outcomes.
- This case highlights the importance of early diagnosis and comprehensive treatment strategies for rare vascular tumors.
