Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Non-linear phenomena in host-parasite interactions.

R M Anderson1, R M May, S Gupta

  • 1Department of Pure and Applied Biology, Imperial College, London University.

Parasitology
|January 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cytogenetic Biomarkers of Radiation Exposure.

Clinical oncology (Royal College of Radiologists (Great Britain))·2019
Same author

A comparison of two mathematical models of the impact of mass drug administration on the transmission and control of schistosomiasis.

Epidemics·2017
Same author

K-complexes, spindles, and ERPs as impulse responses: unification via neural field theory.

Biological cybernetics·2017
Same author

Are patients with pulmonary tuberculosis who are identified through active case finding in the community different than those identified in healthcare facilities?

New microbes and new infections·2016
Same author

Soil-Transmitted Helminths: Mathematical Models of Transmission, the Impact of Mass Drug Administration and Transmission Elimination Criteria.

Advances in parasitology·2016
Same author

Studies of the Transmission Dynamics, Mathematical Model Development and the Control of Schistosome Parasites by Mass Drug Administration in Human Communities.

Advances in parasitology·2016
Same journal

Integrative description of <i>Udonella umgibeli</i> n. sp. (Monopisthocotylea: Udonellidae) as an epibiont of <i>Caligus tetrodontis</i> Barnard, 1948, off the coast of South Africa.

Parasitology·2026
Same journal

Clarifying the taxonomic status of <i>Syphatineria</i> (<i>Africanoxys</i>) <i>cepapi</i> Hugot, 1981 (Nematoda: Oxyuridae) in <i>Paraxerus cepapi</i> Smith, 1836 with new insights into its morphology, ecology and genetics.

Parasitology·2026
Same journal

Major human brain parasites. A narrative review of clinical, diagnostic, and therapeutic strategies.

Parasitology·2026
Same journal

Parasite transmission risk at the urban human-dog-macaque Interface.

Parasitology·2026
Same journal

Morphological characterisation of <i>Echinococcus equinus</i> from lions (<i>Panthera leo</i>) in the greater Kruger National Park, South Africa.

Parasitology·2026
Same journal

<i>Schistosoma mansoni</i> Vaccines: Past, Present, and Future.

Parasitology·2026
See all related articles

Mathematical models reveal non-linear dynamics in host-parasite systems. Control measures like vaccination and chemotherapy show complex impacts on infection, depending on application levels and parasite genetics.

Area of Science:

  • Ecology and Evolutionary Biology
  • Mathematical Biology
  • Parasitology

Background:

  • Examines non-linear dynamics in host-parasite interactions using mathematical models.
  • Investigates control measures including vaccination and chemotherapy, and host immunological responses.
  • Considers effects on parasite transmission, prevalence, and intensity.

Discussion:

  • Control measure effectiveness (vaccination, chemotherapy) is non-linearly related to the magnitude of control effort.
  • Vaccine strategies against malaria (gametocyte vs. sporozoite) require high immunization levels to block transmission.
  • Chemotherapy efficacy against helminths with resistance genes depends critically on application frequency and intensity.

Key Insights:

  • Intermediate application frequency of chemotherapy is optimal for suppressing parasite genotypes with resistance genes.

Related Experiment Videos

  • Host immune responses' effectiveness is inversely related to the target parasite stage's life expectancy.
  • Non-linear relationships govern host-parasite dynamics and the impact of interventions.

    • Outlook:

    • Further modeling can refine understanding of complex host-parasite interactions.
    • Optimizing control strategies requires considering non-linear effects and parasite genetics.
    • Investigating specific parasite life-cycle stages offers insights into intervention effectiveness.