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Rudolph Virchow discovered spindle-shaped cells called fibroblasts in 1858. Inactive fibroblasts, called fibrocytes, become activated by various stimuli, such as growth factors and inflammatory cytokines. Activated fibroblasts play a crucial role in wound healing, inflammation, formation of new blood vessels, and cancer progression. Uncontrolled activation of fibroblasts results in fibrosis, the excess deposition of fibrous tissue, which can lead to scarring and affect normal organs. This...

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MITF Positivity in Atypical Fibroxanthoma

Ben Tallon¹, Trevor W Beer

¹*Dermatopathology Division, Pathlab Bay of Plenty, Tauranga, New Zealand †Skin at Da Vinci Clinic, Tauranga, New Zealand ‡Clinipath Pathology, West Perth, Australia.

The American Journal of Dermatopathology

|January 31, 2016

Summary

No abstract available in PubMed .

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