Effect of Scopolamine Patch Use on Postoperative Voiding Function After Transobturator Slings.

Area of Science:

• Urogynecology
• Surgical Outcomes
• Pharmacology

Background:

• Postoperative nausea and vomiting (PONV) is a common complication after surgical procedures.
• Transobturator tape (TOT) sling procedures are frequently performed for stress urinary incontinence.
• Prophylaxis for PONV may impact other postoperative outcomes.

Purpose of the Study:

• To investigate the effect of preoperative transdermal scopolamine (TDS) patch use on voiding trial success after TOT sling surgery.
• To determine if TDS for PONV prophylaxis influences postoperative urinary function recovery.

Main Methods:

• Retrospective cohort study design.
• Inclusion of adult women undergoing TOT sling procedures without concomitant surgeries.
• Comparison of voiding trial failure rates between women who received a preoperative TDS patch and those who did not.

Main Results:

• A significantly higher proportion of women using TDS patches (54.3%) failed their voiding trial compared to the non-TDS group (7.1%).
• TDS patch use was associated with a 13.8-fold increased risk of voiding trial failure.
• Factors like prior incontinence surgery, older age, and higher BMI amplified the association.

Conclusions:

• Preoperative TDS patch use for PONV prophylaxis may negatively impact voiding trial success post-TOT sling.
• Clinicians should consider the potential for impaired bladder function when prescribing TDS in this patient population.