Related Experiment Video

Updated: Mar 26, 2026

Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers
09:36

Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers

Published on: July 28, 2022

2.7K

Vitamin D Intake in Very Low Birth Weight Infants in Neonatal Intensive Care Unit

Upender K Munshi1, Pauline D Graziano, Kara Meunier

  • 1Department of Pediatrics, Albany Medical Center, NY.

Journal of Pediatric Gastroenterology and Nutrition
|January 31, 2016
PubMed

Insights

Monitoring daily vitamin D intake in neonatal intensive care units improved nutrient achievement for preterm infants. This intervention enhanced vitamin D levels in extremely low birth weight and very low birth weight infants.

Area of Science:

  • Neonatology
  • Pediatric Nutrition
  • Endocrinology

Background:

  • Preterm infants require adequate Vitamin D for growth and bone health.
  • The American Academy of Pediatrics recommends 400 IU of Vitamin D daily for infants.
  • Current achievement rates of this recommendation in neonatal intensive care units are not well-established.

Purpose of the Study:

  • To determine the impact of a daily Vitamin D intake monitoring system on achieving recommended levels in preterm infants.
  • To assess if this monitoring improves Vitamin D intake in different birth weight strata.

Main Methods:

  • Retrospective study of 378 preterm infants (birth weight ≤1500 g) admitted to a neonatal intensive care unit.
  • Infants were divided into two groups: pre-implementation (151 infants) and post-implementation (227 infants) of daily Vitamin D monitoring.
  • Infants were further stratified into extremely low birth weight (<1000 g) and very low birth weight (1000-1500 g) categories.

Main Results:

  • Introduction of daily Vitamin D intake monitoring led to a significant improvement in Vitamin D intake.
  • This improvement was observed in both extremely low birth weight and very low birth weight infant groups.
  • The monitoring system effectively increased the achievement of the recommended 400 IU daily intake.

Conclusions:

  • Implementing a daily Vitamin D intake monitoring system is effective in improving nutrient delivery for preterm infants.
  • This strategy is crucial for ensuring adequate Vitamin D levels in vulnerable neonatal populations.
  • Neonatal intensive care units should consider such monitoring to optimize preterm infant nutrition and health outcomes.

More Related Videos

Transcutaneous Microcirculatory Imaging in Preterm Neonates06:27

Transcutaneous Microcirculatory Imaging in Preterm Neonates

Published on: December 31, 2015

8.6K

Related Concept Videos

Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
8.7K
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
733
Vitamins01:30

Vitamins

Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
2.9K
Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
597
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
460
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
370