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Updated: Mar 26, 2026

Detecting Migration and Infiltration of Neutrophils in Mice
Published on: February 6, 2020
Neutrophils and arthritis: Role in disease and pharmacological perspectives
Victor Fattori1, Flavio A Amaral2, Waldiceu A Verri1
1Departamento de Ciências Patológicas, Centro de Ciências Biológicas, Universidade Estadual de Londrina, Londrina, Paraná, Brazil.
Abstract:
The inflammatory response in the joint can induce an intense accumulation of leukocytes in the tissue that frequently results in severe local damage and loss of function. Neutrophils are essential cells to combat many pathogens, but their arsenal can contribute or aggravate articular inflammation. Here we summarized some aspects of neutrophil biology, their role in inflammation and indicated how the modulation of neutrophil functions could be useful for the treatment of different forms of arthritis.
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