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Comparative study of inorganic elements determined in whole blood from Dmd(mdx)/J mice strain by EDXRF and NAA
M M Redígolo1, I M Sato1, S Metairon2
1Instituto de Pesquisas Energéticas e Nucleares, IPEN - CNEN/SP, Centro de Química e Meio Ambiente, CQMA, Av. Professor Lineu Prestes 2242, 05508-000 São Paulo, SP, Brasil.
Abstract:
Several diseases can be diagnosed observing the variation of specific elements concentration in body fluids. In this study the concentration of inorganic elements in blood samples of dystrophic (Dmd(mdx)/J) and C57BL/6J (control group) mice strain were determined. The results obtained from Energy Dispersive X-ray Fluorescence (EDXRF) were compared with Neutron Activation Analysis (NAA) technique. Both analytical techniques showed to be appropriate and complementary offering a new contribution for veterinary medicine as well as detailed knowledge of this pathology.
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