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Transient Expression in Nicotiana Benthamiana Leaves for Triterpene Production at a Preparative Scale
Published on: August 16, 2018
Lanostane-type triterpenes from the fungal endophyte Scleroderma UFSMSc1 (Persoon) Fries
Liziane M B Morandini1, Alexandre T Neto1, Marcelo Pedroso1
1Universidade Federal de Santa Maria, Departamento de Química, Camobi, Santa Maria, RS, Brazil.
Abstract:
Two lanostane triterpenoids (sclerodols A and B) were isolated from the culture of the Eucalyptus grandis derived from the endophyte Scleroderma UFSM Sc1(Persoon) Fries together with three known compounds: one related triterpenoid lanosta-8,23-dien-3β,25-diol, the disaccharide α,β-trehalose, and the sugar alcohol mannitol. Their structures were elucidated on the basis of 2D NMR, HRME, and single-crystal X-ray diffraction data. The methanol crude extract and the isolated lanostane triterpenoids showed promising anticandidal activities.
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