Heating system of pellet samples integrated with terahertz spectrometer
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Updated: Mar 26, 2026

A Package of Established Analytical Tools to Investigate the Solid-State Alteration of Lipid-Based Excipients
Published on: August 9, 2022
L A Sterczewski1, M P Grzelczak1, E F Plinski1
1Department of Electronics, Wroclaw University of Technology, 27 Wybrzeze Wyspianskiego St., 50-370 Wroclaw, Poland.
Abstract:
This article describes automation of temperature-dependent terahertz spectroscopic experiments. The proposed dual-heater temperature controller based on a cascade proportional-integral-derivative algorithm provides smooth temperature changes in the polyethylene-based pharmaceutical pellet samples. The device has been integrated with a terahertz time-domain spectrometer. Thermodynamic experiments can now be performed without any probe inserted into the measured sample. Selected results of temperature-induced evolution in terahertz spectra are presented.
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