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Updated: Mar 26, 2026

Preclinical Drug Testing in Scalable 3D Engineered Muscle Tissues
Published on: April 7, 2023
[Drug interaction in 63-year-old male sportsman--a case report]
Unlabelled:
We present a case of 63-year-old male with hypertension and hyperlipidaemia, who was an athlete in the "masters category". Because of interaction between amlodipine and simvastatin, in combination with physical activity, the patient reported: muscle pain, weakness of the muscles, dizziness, and confusion. After amlodipine and simvastatin discontinuation, all symptoms resolved rapidly.
Conclusions:
(1) Concomitant use of several drugs by elderly individual patients, the risk of drug--physical activity interactions may occur.
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