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Elevated 68Ga Prostate-Specific Membrane Antigen Activity in Metastatic Non-Small Cell Lung Cancer
Deepa Shetty1, Han Loh, Chuong Bui
1From the *Department of Nuclear Medicine and PET, Nepean Hospital, Penrith; †Sydney Medical School Nepean, University of Sydney, and ‡Department of Oncology, Nepean Hospital, Penrith, New South Wales, Australia.
Abstract:
A 71-year-old man with a background of treated stage IIIB non-small cell lung cancer was referred for Ga prostate-specific membrane antigen (PSMA) PET/CT for staging of prostate cancer. In addition to the PSMA uptake in the known prostate malignancy, the study also demonstrated increased PSMA uptake in an enlarging left lower lobe lung mass with diffusely increased PSMA uptake in an enlarged thyroid gland and bilateral enlarged supraclavicular lymph nodes. Fine-needle aspiration biopsy of the thyroid gland and a left supraclavicular lymph node demonstrated metastatic adenocarcinoma from a primary lung cancer.
