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Related Experiment Video

Updated: Mar 26, 2026

The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy rNAION
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RUPTURED RETINAL ARTERIAL MACROANEURYSM ON THE OPTIC DISK.

Ehsan Rahimy1, Brian C Doyle, Gary C Brown

  • 1Wills Eye Hospital Retina Service, Philadelphia, Pennsylvania.

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Summary
This summary is machine-generated.

An occult optic disk macroaneurysm caused vision loss and hemorrhage. Multimodal imaging confirmed the diagnosis after initial examination missed it due to overlying bleeding.

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Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Retinal Vascular Diseases

Background:

  • Optic disk macroaneurysms are rare vascular abnormalities.
  • They can present with vision loss due to associated hemorrhage.
  • Diagnosis can be challenging due to overlying retinal pathology.

Observation:

  • A 54-year-old woman presented with decreased vision and multi-layered retinal hemorrhage.
  • Fundoscopic examination did not reveal the source of bleeding.
  • Fluorescein angiography identified an occult optic disk macroaneurysm.

Findings:

  • Optical coherence tomography (OCT) after hemorrhage resolution showed a thrombosed macroaneurysm.
  • An adjacent ring of exudate was noted on OCT.
  • The macroaneurysm was initially obscured by hemorrhage.

Implications:

  • Optic disk macroaneurysms should be considered in cases of unexplained macular hemorrhage.
  • Multimodal imaging is crucial for diagnosing occult optic disk macroaneurysms.
  • Early detection can guide appropriate management and prevent vision loss.