An update on polysaccharide-based nanomaterials for antimicrobial applications
Divya Arora1,2, Nisha Sharma1,2, Vishal Sharma1,2
1Quality Control & Quality Assurance Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu, , 180001, India.
Applied Microbiology and Biotechnology
|February 3, 2016
Summary
Nanocarrier drug delivery systems using polysaccharides offer a promising solution to combat infectious diseases and antimicrobial resistance. These systems enhance drug efficacy, enable targeted delivery, and improve material properties.
Area of Science:
- Biomaterials Science
- Nanotechnology
- Pharmaceutical Sciences
Background:
- Antimicrobial agents face challenges including multi-drug resistance and adverse side effects.
- Nanocarrier-based drug delivery systems utilizing polysaccharides are gaining significant attention.
- Polysaccharides can enhance the efficacy of antimicrobial agents through adsorption, entrapment, or linkage.
Purpose of the Study:
- To review the therapeutic applications of nanocarrier-based drug delivery systems using polysaccharides for antimicrobial purposes.
- To highlight the advantages of these systems in overcoming limitations of conventional antimicrobial therapies.
Main Methods:
- Literature review focusing on nanocarrier-based drug delivery systems.
- Analysis of studies investigating polysaccharide-based nanocarriers for antimicrobial applications.
- Evaluation of systems for enhanced drug efficacy, targeted delivery, and material synthesis.
Main Results:
- Nanocarrier systems increase drug surface area, leading to enhanced efficacy.
- Targeted drug delivery is achievable with polysaccharide-based nanocarriers.
- These systems contribute to the development of packaging materials with improved antimicrobial properties and mechanical strength.
Conclusions:
- Nanocarrier-based drug delivery systems using polysaccharides show significant potential for therapeutic antimicrobial applications.
- These advanced systems offer solutions to multi-drug resistance and improve drug delivery efficiency.
- Further research into polysaccharide nanocarriers can lead to innovative antimicrobial strategies and materials.
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