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Summary
Hematological studies reveal significant variations in normal blood parameters across diverse populations due to lifestyle and methodology. This research highlights the need for updated reference ranges, especially considering industrialization
Area of Science:
- Hematology
- Clinical Pathology
- Population Health
Context:
- Hematological reference ranges vary significantly across different populations.
- Factors such as social, environmental, nutritional, and methodological differences contribute to these variations.
- Existing studies lack standardized parameters for defining 'normal' in diverse groups.
Purpose:
- To review existing hematological studies from Brazil and Latin America.
- To identify key factors influencing variations in hematological parameters.
- To lay the groundwork for future research on industrialization's impact on hematological norms.
Summary:
- A review of Brazilian and Latin-American hematological studies revealed substantial differences in normal parameters.
- These variations are attributed to social, environmental, nutritional, methodological, and individual factors (age, sex, race, occupation).
- Three Brazilian studies were selected to demonstrate the wide range of 'normal' values.
Impact:
- Highlights the critical need for population-specific hematological reference ranges.
- Provides a basis for investigating the effects of environmental changes, like industrialization, on blood parameters.
- Emphasizes the importance of standardized methodologies in hematological research.