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Related Experiment Video

Updated: May 2, 2026

An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP
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An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP

Published on: January 28, 2010

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Depression and postoperative complications: an overview.

Mohamed M Ghoneim1, Michael W O'Hara2

  • 1Department of Anesthesia - 6JCP, University of Iowa Hospitals and Clinics, Iowa City, IA, 52242, USA. mohamed-ghoneim@uiowa.edu.

BMC Surgery
|February 3, 2016
PubMed
Summary

Depression significantly increases surgical patient morbidity and mortality. Early identification and interventions like counseling are crucial for improving outcomes and recovery after surgery.

Related Experiment Videos

Last Updated: May 2, 2026

An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP
14:56

An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP

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Area of Science:

  • Medical research
  • Surgical outcomes
  • Mental health in medicine

Background:

  • Depression is a frequent complication of surgery, increasing patient morbidity and mortality.
  • The interplay between depression, anesthesia, and surgery poses significant health risks.

Purpose of the Study:

  • To review the impact of depression on surgical patient outcomes.
  • To highlight depression as a risk factor for postoperative complications and mortality.

Main Methods:

  • Literature search of electronic databases including PubMed.
  • Keywords included "depression" paired with surgical terms and postoperative complications.
  • Review of studies on depression's impact on infection, pain, delirium, and quality of life.

Main Results:

  • Depression is linked to increased postoperative infections, mortality, and cognitive impairment.
  • It exacerbates pain, predicts chronic postsurgical pain, and increases delirium risk.
  • Depression is associated with lower quality of life and higher mortality in intensive care unit patients.

Conclusions:

  • Depression is a common cause of morbidity across various surgical conditions.
  • Screening tools like the Patient Health Questionnaire-9 can identify depression.
  • Counseling interventions show promise but require further clinical trial validation.