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Pathology of Fungal Rhinosinusitis: A Review

Kathleen T Montone1

  • 1Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, 3400 Spruce Street, 6 Founders, Philadelphia, PA, 19104, USA. kmontone@mail.med.upenn.edu.

Head and Neck Pathology
|February 3, 2016
PubMed

Insights

Fungal rhinosinusitis (FRS) presents diversely and is classified by fungal invasion into tissue. This review focuses on the pathological classification of FRS, aiding in understanding its varied presentations.

Area of Science:

  • Pathology
  • Mycology
  • Otolaryngology

Background:

  • Fungal rhinosinusitis (FRS) encompasses a range of conditions with differing clinical, histological, and biological characteristics.
  • FRS can manifest as acute or chronic infections.
  • Classification is primarily based on the presence or absence of fungal invasion into host tissues.

Purpose of the Study:

  • To review and elucidate the pathological classification of fungal rhinosinusitis.
  • To provide a framework for understanding the spectrum of FRS based on tissue invasion.

Main Methods:

  • Literature review of pathological classifications of FRS.
  • Analysis of diagnostic criteria for invasive versus non-invasive fungal sinusitis.

Main Results:

  • FRS is broadly categorized into non-invasive and invasive forms.
  • The distinction between invasive and non-invasive FRS is critical for determining disease significance and management.

Conclusions:

  • Pathological classification is essential for accurately diagnosing and managing fungal rhinosinusitis.
  • Understanding the invasive potential of fungi in the sinuses guides clinical decision-making.
Keywords:
Acute invasive fungal rhinosinusitisAllergic fungal rhinosinusitisAllergic mucinAspergillusFungal ballRhinosinusitis

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