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Newly Described Tumor Entities in Sinonasal Tract Pathology

Justin A Bishop^1,2

¹Department of Pathology, The Johns Hopkins Medical Institutions, The Johns Hopkins University School of Medicine, 401 N. Broadway, Weinberg 2249, Baltimore, MD, 21231, USA. jbisho16@jhmi.edu.

Head and Neck Pathology

|February 3, 2016

Abstract:

Surgical pathology of the sinonasal tract (nasal cavity and paranasal sinuses) is extremely challenging due in part to the tremendous diversity of tumor types that may arise in this region. Compounding the difficulty, a number of new sinonasal tumor entities have been recently described, and pathologists may not yet be familiar with these neoplasms. This manuscript will review the clinicopathologic features of some of the newly described sinonasal tumor types: NUT midline carcinoma, HPV-related carcinoma with adenoid cystic-like features, SMARCB1 (INI-1) deficient sinonasal carcinoma, biphenotypic sinonasal sarcoma, and renal cell-like adenocarcinoma.

Keywords:

Biphenotypic sinonasal sarcoma HPV-related carcinoma with adenoid cystic-like features NUT midline carcinoma Renal cell-like adenocarcinoma SMARCB1 (INI-1) deficient sinonasal carcinoma

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