Association between obesity measures and albuminuria: A population-based study
1Department of Endocrinology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yanjiang West Road, Guangzhou, 510120, People' s Republic of China.
Journal of Diabetes and Its Complications
|February 3, 2016
Summary
Obesity measures like BMI and waist circumference are linked to albuminuria in Chinese adults. Higher obesity levels correlate with increased albuminuria, indicating a risk for kidney issues.
Area of Science:
- Nephrology
- Endocrinology
- Public Health
Background:
- Obesity is a growing concern globally, with potential links to microvascular complications.
- Albuminuria is an early marker of kidney damage and a predictor of cardiovascular disease.
Purpose of the Study:
- To investigate the association between various obesity indicators and albuminuria in a Chinese population.
- To determine if obesity measures predict increased urinary albumin excretion.
Main Methods:
- A cross-sectional study of 8600 Chinese adults aged 40+ in Guangzhou.
- Measured urinary albumin-to-creatinine ratio (ACR) to assess albuminuria.
- Analyzed correlations between body mass index (BMI), waist circumference, body fat, and ACR.
Main Results:
- Significant correlations were found between BMI, waist circumference, body fat, and ACR (P<0.01).
- Albuminuria prevalence increased with higher quartiles of BMI, waist circumference, and body fat (P for trend<0.0001).
- Obesity indicators remained significant predictors of albuminuria after adjusting for metabolic factors.
Conclusions:
- Obesity measures are independently associated with albuminuria in middle-aged and elderly Chinese individuals.
- Findings suggest obesity contributes to kidney microvascular changes in this population.
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