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Comparing the effects of Bentonite & Calendula on the improvement of infantile diaper dermatitis: A randomized
Mansoreh Mahmoudi, Mohsen Adib-Hajbaghery1, Mahdi Mashaiekhi
1Department of Medical-Surgical Nursing, Faculty of Nursing & Midwifery, Kashan, Kashan, Iran.
Insights
Bentonite cream demonstrated a faster and more effective healing effect for infantile diaper dermatitis compared to Calendula cream. This study highlights Bentonite as a superior topical treatment for improving infant skin inflammation.
Area of Science:
- Dermatology
- Pediatrics
- Pharmacology
Background:
- Infantile diaper dermatitis is a prevalent acute inflammatory skin condition in infants.
- It affects the skin in the diaper area, causing discomfort and requiring effective treatment.
Purpose of the Study:
- To compare the efficacy of topical Bentonite cream versus Calendula cream in treating infantile diaper dermatitis.
- To evaluate the speed and completeness of lesion improvement with each treatment.
Main Methods:
- A double-blind, randomized controlled trial involving 100 infants with diaper dermatitis.
- Participants were divided into two groups (50 each), receiving either Bentonite or Calendula cream.
- Improvement was assessed by trained mothers and clinical observation at baseline and after three days.
Main Results:
- Bentonite cream showed significantly faster improvement, with 88% of lesions improving within six hours compared to 54% for Calendula (P<0.001).
- Complete lesion improvement within three days was observed in 86% of infants treated with Bentonite versus 52% with Calendula (P<0.001).
- The risk ratio for improvement within six hours was 2.99-fold higher for Bentonite.
Conclusions:
- Bentonite cream exhibits a faster and more potent healing effect on infantile diaper dermatitis than Calendula cream.
- Topical Bentonite offers a more effective treatment option for improving this common infant skin condition.
Background & Objectives:
Infantile diaper dermatitis is a common, acute inflammatory reaction of the skin around diaper among infants. This study was undertaken to compare the effect of topical application of Bentonite and Calendula creams on the improvement of infantile diaper dermatitis.
Methods:
This double blind randomized controlled trial was undertaken on 100 patients of infantile diaper dermatitis. The 100 participants were randomly assigned into two groups of 50 each, and were prescribed the coded medicine. The mothers were trained to apply the cream and level of improvement was judged by observing the affected area on the first visit and then after three days of receiving treatment.
Results:
The mean age of infants was 6.45±5.53 months in Calendula group and 7.35±6.28 months in Bentonite group. Overall, 88 per cent of lesions in the Bentonite group started improving in the first six hours while this rate was 54 per cent in Calendula group (P<0.001). The risk ratio for the improvement in the first six hours was 2.99 folds in the Bentonite group. Also, lesions in 86 per cent infants in the Bentonite group and 52 per cent in the Calendula group were completely improved in the first three days after treatment (P<0.001).
Interpretation & Conclusions:
Our results showed that in comparison with Calendula, Bentonite had faster healing effect and was more effective on the improvement of infantile diaper dermatitis (IRCT ID: IRCT 2012112811593N1).
