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Updated: Mar 26, 2026

Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions
Published on: January 26, 2024
Characterization of Nonribosomal Peptide Synthetases with NRPSsp
1Bioinformatics Service, Nucleus, University of Salamanca (USAL), Edificio I+D+i, C/ Espejo 2, Salamanca, 37007, Spain. cprietos@usal.es.
Abstract:
Bioinformatic sequence analysis allows the functional characterization of newly sequenced proteins. Nonribosomal peptide synthetases (NRPSs) are multi-modular enzymes involved in the biosynthesis of natural products. The current omics era has enabled the exponential growth of the sequenced NRPS, and it is important to characterize the final product of these synthetases. Here, how to achieve the prediction of substrates which bind to adenylation domains in NRPS with NRPSsp (www.nrpssp.com) bioinformatic tool is described.
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