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Association of carbon monoxide levels with allergic diseases in children

Jihyun Kim1, Youngshin Han, Sung Chul Seo

  • 1Department of Pediatrics, Samsung Medical Center, Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Allergy and Asthma Proceedings
|February 3, 2016
PubMed

Insights

Exposure to carbon monoxide (CO) in infancy is linked to a higher risk of developing allergic rhinitis. Higher CO levels in the past year also increased the likelihood of current atopic dermatitis symptoms in children.

Area of Science:

  • Environmental Health
  • Pediatric Allergy
  • Epidemiology

Background:

  • Air pollution is a suspected factor in the development and worsening of allergic diseases.
  • Understanding the specific impact of air pollutants on childhood allergies is crucial for public health.

Purpose of the Study:

  • To examine the link between early-life exposure to outdoor air pollution and the development of allergic diseases.
  • To assess the association between residential air pollution levels and current allergy symptoms in children.

Main Methods:

  • A nationwide cross-sectional survey of 6- to 7-year-old children was conducted.
  • Data from 1828 infants and 1894 children living near air quality monitoring sites were analyzed.
  • Allergic disease prevalence was assessed via questionnaires and pediatrician examinations; air pollutant data (SO2, NO2, O3, CO, PM) were obtained.

Main Results:

  • A 100 ppb increase in mean daily carbon monoxide (CO) during infancy correlated with a 1.10 odds ratio for lifetime allergic rhinitis.
  • A 1 ppm increase in annual average CO over the past 12 months showed an 8.11 odds ratio for current atopic dermatitis.
  • No significant associations were found for other measured air pollutants.

Conclusions:

  • Infant exposure to elevated carbon monoxide (CO) levels elevates the risk for allergic rhinitis.
  • Increased CO exposure in the preceding year is associated with a higher risk of current atopic dermatitis symptoms in children.
Abstract

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