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Tead and AP1 Coordinate Transcription and Motility

Xiangfan Liu1, Huapeng Li1, Mihir Rajurkar1

  • 1Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605, USA.

Cell Reports
|February 3, 2016
PubMed
Summary

Tead4 transcription factors cooperate with AP1 to drive cancer cell migration and invasion. This study reveals a key regulatory mechanism for Tead- and AP1-controlled gene expression in tumors.

Keywords:
AP1Teadinvasiontranscriptional regulation

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