Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Role of Hippocampus in Memory01:19

Role of Hippocampus in Memory

2.0K
The hippocampus, a critical brain structure, plays an essential role in memory processing, particularly in the formation and retrieval of memory. This small, seahorse-shaped region is located within the medial temporal lobe, with one hippocampus in each brain hemisphere. Experimental studies involving lesions in the hippocampi of rats have demonstrated significant impairments in tasks such as object recognition and maze navigation, indicating the hippocampus involvement in both recognition and...
2.0K
Role of Cerebellum and Prefrontal Cortex in Memory01:14

Role of Cerebellum and Prefrontal Cortex in Memory

1.4K
The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...
1.4K
Implicit Memories01:24

Implicit Memories

568
Implicit memories, also known as non-declarative memories, are long-term memories that function outside of conscious awareness. These memories influence behavior and skills without explicit knowledge. This type of memory is evident in tasks like playing tennis, snowboarding, and texting. Implicit memory has three subsystems: procedural memory, conditioning, and priming. This type of memory is essential in various activities, from everyday tasks to specialized skills.
One key aspect of implicit...
568
Higher Mental Functions of Brain: Learning and Memory01:26

Higher Mental Functions of Brain: Learning and Memory

2.3K
Memory is one of the most vital higher mental functions of the brain. Memory is closely related to learning because it enables us to retain information and experiences from our past to use them in our present life. It also helps us to remember facts, events, and skills, such as riding a bike or swimming. There are two types of memory — declarative memory, which involves memorizing facts or events, and procedural memory, which enables us to remember how to do something like writing or...
2.3K
Long-Term Memory01:18

Long-Term Memory

837
Long-term memory is a relatively permanent type of memory, capable of storing vast amounts of information over extended periods. Its storage capacity is generally considered unlimited.
Long-term memory can be categorized into two primary types: explicit and implicit memory. Explicit memory, also known as declarative memory, involves the conscious recollection of information that we deliberately try to remember, recall, and articulate. This type of memory encompasses specific facts, events, and...
837
Interference and Decay01:16

Interference and Decay

570
Forgetting is a complex cognitive phenomenon influenced by several factors, among which interference and decay are particularly prominent. These processes explain why individuals often struggle to retrieve specific information from memory, leading to lapses in recall that can be observed in everyday situations.
Interference occurs when competing memories hinder the retrieval of particular information. It can be classified into two types: proactive and retroactive interference. Proactive...
570

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

It's not just the phase: Frequency-dependent tuning of neuronal firing.

PLoS biology·2026
Same author

Inter-subject correlations and their behavioral associations vary across movies: Implications for generalizability.

bioRxiv : the preprint server for biology·2026
Same author

Action information is integrated into entorhinal representations of conceptual space and is reflected in eye movements.

PLoS biology·2026
Same author

Pre-stimulus alpha power modulates trial-by-trial variability in theta rhythmic multisensory entrainment strength and theta-induced memory effect.

Communications psychology·2026
Same author

Efficient coding in working memory is adapted to the structure of the environment.

Cell reports·2026
Same author

Locomotion-dependent use of geometric and body cues in humans mapping 3D space.

Proceedings of the National Academy of Sciences of the United States of America·2025

Related Experiment Video

Updated: Mar 26, 2026

Tuning in the Hippocampal Theta Band In Vitro: Methodologies for Recording from the Isolated Rodent Septohippocampal Circuit
11:37

Tuning in the Hippocampal Theta Band In Vitro: Methodologies for Recording from the Isolated Rodent Septohippocampal Circuit

Published on: August 2, 2017

10.4K

Hippocampal-Prefrontal Theta Oscillations Support Memory Integration.

Alexander R Backus1, Jan-Mathijs Schoffelen2, Szabolcs Szebényi3

  • 1Radboud University, Donders Institute for Brain, Cognition and Behaviour, 6525 Nijmegen, the Netherlands.

Current Biology : CB
|February 3, 2016
PubMed
Summary

Hippocampal theta oscillations are key for integrating memories, enabling inferential reasoning. This brain activity enhances communication between the hippocampus and medial prefrontal cortex (mPFC) for complex behaviors.

More Related Videos

Optogenetic Entrainment of Hippocampal Theta Oscillations in Behaving Mice
07:33

Optogenetic Entrainment of Hippocampal Theta Oscillations in Behaving Mice

Published on: June 29, 2018

12.4K
Automatic Detection of Highly Organized Theta Oscillations in the Murine EEG
09:35

Automatic Detection of Highly Organized Theta Oscillations in the Murine EEG

Published on: March 10, 2017

9.8K

Related Experiment Videos

Last Updated: Mar 26, 2026

Tuning in the Hippocampal Theta Band In Vitro: Methodologies for Recording from the Isolated Rodent Septohippocampal Circuit
11:37

Tuning in the Hippocampal Theta Band In Vitro: Methodologies for Recording from the Isolated Rodent Septohippocampal Circuit

Published on: August 2, 2017

10.4K
Optogenetic Entrainment of Hippocampal Theta Oscillations in Behaving Mice
07:33

Optogenetic Entrainment of Hippocampal Theta Oscillations in Behaving Mice

Published on: June 29, 2018

12.4K
Automatic Detection of Highly Organized Theta Oscillations in the Murine EEG
09:35

Automatic Detection of Highly Organized Theta Oscillations in the Murine EEG

Published on: March 10, 2017

9.8K

Area of Science:

  • Cognitive Neuroscience
  • Neurophysiology
  • Memory Research

Background:

  • Inferential reasoning relies on integrating separate memories, a fundamental cognitive process.
  • The hippocampus and medial prefrontal cortex (mPFC) are critical for memory integration.
  • Theta oscillations are implicated in memory, but their role in integration is unclear.

Purpose of the Study:

  • To investigate the electrophysiological mechanisms of memory integration.
  • To explore the role of hippocampal theta oscillations in memory integration and inferential reasoning.

Main Methods:

  • Magnetoencephalography (MEG) was used to record brain activity during an inference task.
  • Advanced source reconstruction techniques estimated oscillatory signals from the hippocampus.
  • Theta power and coherence between brain regions were analyzed.

Main Results:

  • Increased hippocampal theta power during memory encoding predicted successful memory integration.
  • Enhanced theta coherence was observed between the hippocampus and the mPFC.
  • These findings link hippocampal theta activity to the integration of memory representations.

Conclusions:

  • Hippocampal theta oscillations play a crucial role in memory integration.
  • These oscillations may facilitate communication between the hippocampus and mPFC, supporting complex cognition.
  • Findings advance understanding of memory-based decision-making and knowledge acquisition.