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Identification and Protection of the Recurrent Laryngeal Nerve during Transoral Robotic Thyroidectomy
Published on: October 24, 2025
Voice Changes after Late Recurrent Laryngeal Nerve Identification Thyroidectomy.
Ezzeddin Elsheikh1, Amal Saeed Quriba2, Mohammad Waheed El-Anwar3
1Otorhinolaryngology Head and Neck Surgery Department, Faculty of Medicine, Zagazig University, Egypt.
Thyroidectomy using a late recurrent laryngeal nerve (RLN) identification technique resulted in minimal, temporary voice changes. These voice issues resolved within months, comparable to other surgeries, indicating the technique is safe for voice preservation.
Area of Science:
- Otolaryngology
- Endocrine Surgery
- Vocal Cord Function
Background:
- Thyroidectomy carries risks of recurrent laryngeal nerve (RLN) injury, potentially causing voice changes.
- The late RLN identification technique aims to minimize operative trauma during thyroid dissection.
Purpose of the Study:
- To evaluate voice alterations in patients undergoing thyroidectomy with a late recurrent laryngeal nerve (RLN) identification technique, specifically when the nerve was not injured.
- To compare voice outcomes between hemithyroidectomy and total thyroidectomy subgroups and a control group.
Main Methods:
- A prospective study involving 64 patients undergoing thyroidectomy with late RLN identification.
- Voice assessment using a standardized protocol and Voice Problem Self-Assessment Scale at multiple postoperative intervals (1 week, 3 months, 6 months).
- Comparison with a control group of 20 patients who underwent other extracervical surgeries.
Main Results:
- Temporary dysphonia and acoustic deviations (fundamental frequency, noise-to-harmonic ratio, maximal phonation time) were observed at 1 week post-surgery.
- These voice changes significantly improved by 3 months and were non-significant by 6 months post-surgery.
- Patient-reported voice problems also showed significant worsening only at 1 week post-surgery, returning to baseline later.
Conclusions:
- Thyroidectomy employing a late RLN identification technique, without nerve injury, leads to transient and mild voice changes.
- These voice changes are comparable to those seen after other non-neck surgeries.
- The late RLN identification method is a voice-sparing approach in thyroid surgery.
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