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Related Experiment Video

Updated: Mar 26, 2026

Robot-assisted Partial Splenectomy
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Long-term outcomes after pediatric splenectomy.

Topi T Luoto1, Mikko P Pakarinen1, Antti Koivusalo1

  • 1Section of Pediatric Surgery, Pediatric Liver and Gut Research Group, Children's Hospital, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.

Surgery
|February 3, 2016
PubMed
Summary

Long-term outcomes after pediatric splenectomy show that postsplenectomy sepsis is rare and linked to immunodeficiency. Portal vein thrombosis (PVT) was not observed, but retained accessory spleen occurred in 7% of cases.

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Area of Science:

  • Pediatric Surgery
  • Hematology
  • Immunology

Background:

  • Splenectomy is a common procedure in children and adolescents, primarily for hematologic conditions.
  • Long-term complications such as sepsis, portal vein thrombosis (PVT), and retained accessory spleen require thorough investigation.

Purpose of the Study:

  • To analyze the long-term outcomes of splenectomy in pediatric patients.
  • To assess the incidence of sepsis, PVT, and retained accessory spleen after splenectomy.

Main Methods:

  • A cohort of 141 children undergoing open or laparoscopic splenectomy between 1991 and 2010 was followed.
  • Nationwide registries were used to track septic infections, PVT, and mortality.
  • Patients underwent questionnaires and ultrasonography for follow-up assessments.

Main Results:

  • Postsplenectomy sepsis occurred in 8% of patients, predominantly those with underlying immunodeficiency, and was associated with high mortality.
  • No cases of portal vein thrombosis (PVT) were observed.
  • A retained accessory spleen was identified in 7% of patients, with a slightly higher incidence after laparoscopic procedures.

Conclusions:

  • Postsplenectomy sepsis in children is strongly associated with immunodeficiency and carries a significant mortality risk.
  • The risk of portal vein thrombosis (PVT) after splenectomy appears low in this pediatric cohort.
  • Retained accessory spleen is a notable complication, occurring more frequently after laparoscopic splenectomy.