[Regression of human arteriosclerosis]

An account is given of possibilities and mechanisms of regression of arteriosclerosis. Reference is made to animal experiments and to angiographic investigations of man, and the assumption is derived that even in man arteriosclerosis is to a certain extent capable of regression. This view applies preferentially to lipidous alterations. A distinction is made between two mechanisms underlying regression. One of them is attributed to reduction of existing hypercholesterolaemia, while the other is related to regression via action of so far unknown wall factors, without lowering of blood cholesterol.