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Published on: December 6, 2016
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Obstructive Sleep Apnoea and Atrial Fibrillation
Ling Zhang1, Yuemei Hou2, Sunny S Po3
1Cardiovascular Centre, First Affiliated Hospital of Xinjiang Medical University, Xinjiang, China;
Arrhythmia & Electrophysiology Review
|February 3, 2016
Summary
Obstructive sleep apnea (OSA) is linked to atrial fibrillation (AF) initiation and recurrence. Treating OSA with CPAP may improve AF management and reduce patient relapse.
Area of Science:
- Cardiology
- Sleep Medicine
- Internal Medicine
Background:
- Atrial fibrillation (AF) is a prevalent cardiac arrhythmia with significant health impacts.
- Obstructive sleep apnea (OSA) frequently co-exists in AF patients.
- Evidence indicates OSA is independently associated with AF development and persistence.
Purpose of the Study:
- To review the pathophysiological mechanisms linking OSA to AF.
- To discuss current and novel therapeutic strategies for patients with comorbid OSA and AF.
Main Methods:
- Literature review of studies investigating the relationship between OSA and AF.
- Analysis of pathophysiological pathways.
- Evaluation of treatment outcomes for AF in OSA patients.
Main Results:
- OSA is associated with AF initiation and maintenance, independent of obesity and hypertension.
- Untreated OSA leads to higher AF recurrence rates despite standard treatments like medications, cardioversion, and ablation.
- Continuous positive airway pressure (CPAP) therapy shows promise in improving AF control in OSA patients.
Conclusions:
- OSA is a significant contributing factor to AF.
- Effective management of OSA is crucial for improving AF treatment outcomes.
- Further research into combined OSA and AF therapies is warranted.
Keywords:
Atrial fibrillationapnoea–hypopnea indexautonomic nervous systemcontinuous positive airway pressureobstructive sleep apnoeaMore Related Videos
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