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Published on: May 10, 2024
Recurrent wheezing in children
Laura Tenero1, Michele Piazza1, Giorgio Piacentini1
1Department of Life and Reproduction Sciences, Pediatrics Section, University of Verona, Verona, Italy.
Insights
Identifying preschool children at risk for developing asthma is challenging. This review explores recent advancements in diagnosing and treating recurrent wheezing in children to improve long-term outcomes.
Area of Science:
- Pediatric Pulmonology
- Asthma Research
- Childhood Respiratory Diseases
Background:
- Recurrent wheezing affects approximately one-third of children by age five, leading to significant morbidity.
- Early identification of children at risk for developing asthma is crucial for effective treatment and prevention, but remains limited in preschool years.
Purpose of the Study:
- To review recent developments in the diagnosis and treatment of recurrent pediatric wheezing.
- To address the challenges in identifying stable phenotypes for accurate risk assessment and personalized treatment plans.
Main Methods:
- Literature review of recent studies on pediatric recurrent wheezing.
- Analysis of diagnostic criteria and treatment strategies for childhood asthma.
- Evaluation of proposed phenotypes for recurrent wheezing in children.
Main Results:
- Current methods for identifying at-risk preschool children for asthma development have limitations.
- Proposed phenotypes for recurrent wheezing often lack stability, leading to potential over- or underestimation of symptom characteristics.
- Recent research focuses on refining diagnostic tools and therapeutic approaches for pediatric wheezing.
Conclusions:
- Accurate identification of preschool children with recurrent wheezing who are at risk for developing asthma requires further research.
- Developing stable phenotypes is essential for personalized treatment and improved long-term outcomes in pediatric asthma.
- Advancements in diagnosis and treatment offer potential for better management of recurrent wheezing in children.
Abstract:
Recurrent wheezing have a significant morbidity and it's estimated that about one third of school-age children manifest the symptom during the first 5 years of life. Proper identification of children at risk of developing asthma at school age may predict long-term outcomes and improve treatment and preventive approach, but the possibility to identify these children at preschool age remains limited. For many years authors focused their studies to identify early children with recurrent wheezing at risk to develop asthma at school age. Different phenotypes have been proposed for a more precise characterization and a personalized plan of treatment. The main criticism concerns the inability to define stable phenotypes with the risk of overestimating or underestimating the characteristics of symptoms in these children. The aim of this review is to report the recent developments on the diagnosis and treatment of recurrent paediatric wheezing.
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