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Listeria monocytogenes Endovascular Graft Infection

Scott K Heysell1, Molly A Hughes1

  • 1Department of Medicine, Division of Infectious Diseases and International , University of Virginia School of Medicine , Charlottesville.

Open Forum Infectious Diseases
|February 3, 2016
PubMed

Insights

This case study details an alternative treatment for Listeria monocytogenes endovascular graft infection, focusing on graft retention and antibiotics. It highlights a successful lifelong suppressive antibiotic regimen for this rare infection.

Area of Science:

  • Infectious Diseases
  • Vascular Surgery
  • Microbiology

Background:

  • Endovascular graft infections are serious complications requiring prompt management.
  • Surgical resection is the standard treatment for Listeria monocytogenes endovascular graft infections.
  • Alternative strategies are needed for patients unsuitable for resection.

Purpose of the Study:

  • To present a case of Listeria monocytogenes endovascular graft infection managed without surgical resection.
  • To describe an alternative treatment approach involving graft retention and antibiotic therapy.
  • To review the characteristics and management of this rare clinical entity.

Main Methods:

  • Case report of a patient with Listeria monocytogenes endovascular graft infection.
  • Treatment involved graft retention, intensive antibiotic induction, and lifelong suppressive antibiotics.
  • Review of epidemiological, pathological, and clinical features of similar cases.

Main Results:

  • Successful management of Listeria monocytogenes endovascular graft infection with graft retention.
  • Demonstration of a lifelong suppressive antibiotic course as a viable alternative to resection.
  • Detailed review of the unique features of this infection.

Conclusions:

  • Graft retention with prolonged antibiotic therapy can be an effective alternative for Listeria monocytogenes endovascular graft infections.
  • This approach may be suitable for select patients who are not candidates for surgical intervention.
  • Further research into non-resectional management of graft infections is warranted.
Keywords:
Listeria monocytogenesaneurysmdoxycyclineendovascular graft

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