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Hypertension and aging

Thomas W Buford1

  • 1Department of Aging and Geriatric Research, University of Florida, Gainesville, FL 32611, USA.

Ageing Research Reviews
|February 3, 2016
PubMed

Insights

Hypertension in older adults poses significant risks beyond cardiovascular disease, including dementia and physical disability. Understanding these multi-dimensional risks is crucial for effective treatment strategies in elderly populations.

Area of Science:

  • Gerontology
  • Cardiovascular Medicine
  • Neurology

Background:

  • Hypertension is highly prevalent in older adults.
  • Traditional focus on cardiovascular risks overlooks other serious health issues.
  • Collateral effects like dementia, disability, and falls are gaining attention.

Purpose of the Study:

  • To review the multi-dimensional risks of hypertension in the elderly.
  • To discuss potential treatment strategies for late-life hypertension.
  • To identify future research areas for improved care.

Main Methods:

  • Literature review of hypertension in older adults.
  • Analysis of common mechanisms linking aging and hypertension.
  • Synthesis of cardiovascular and collateral risks.

Main Results:

  • Hypertension in older adults increases risks for dementia, physical disability, and falls/fractures.
  • Mechanisms like inflammation, oxidative stress, and endothelial dysfunction contribute to these risks.
  • Late-life hypertension has significant cardiovascular and collateral consequences.

Conclusions:

  • Older adults face diverse health risks from hypertension, extending beyond cardiovascular concerns.
  • Addressing inflammation, oxidative stress, and endothelial dysfunction may mitigate risks.
  • Further research is needed to optimize care for elderly hypertension patients.

Keywords:
AntihypertensiveBlood pressureCardiovascularCognitionDisabilityFalls

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